Anitimicrobial Susceptibility Pattern of Acinetobacter Baumanni at Tertiary Care Hospital in Lahore Pakistan

Abstract

Objective: The aim of study was to check the Anitimicrobial Susceptibility Pattern of Acinetobacter baumannii at tertiary care hospital in lahore Pakistan.
Methodology: Data from clinical specimens of patients with Acinetobacter baumannii infection were retrospectively studied. Standard microbiological techniques were used to screen for antibiotic susceptibility, and the results were then examined to identify patterns of resistance.
Results: Out of 50 clinical isolates of Acinetobacter baumannii, the highest infection rate (52%) was observed in patients above 51 years of age, with a slight female predominance (54%). Alarming levels of resistance were recorded against commonly used antibiotics: 92% to ciprofloxacin, 80% to meropenem, 70% to imipenem, and 72% to gentamicin. Only 24%, 8%, 6%, and 16% of isolates, respectively, remained sensitive to these antibiotics. No significant association was found between gender and resistance patterns for any of the tested drugs (p > 0.05). These findings indicate a high prevalence of multidrug-resistant A. baumannii strains in the hospital setting, underscoring the urgent need for improved antimicrobial stewardship.
Conclusion: The study spotlighted Acinetobacter baumannii’s antibiotic susceptibility pattern at a tertiary care facility in Lahore, Pakistan. In order to address the growing problem of antibiotic resistance, these findings are crucial for directing antimicrobial stewardship initiatives and empirical treatment decisions.